With increasing maternal age, the chances of observing trisomies increase significantly. Increasing paternal age is associated with de novo point mutations. Why?

Answers

Answer 1

Answer:

Mother: higher risk of an improper chromosome division

Father: higher risk to suffer point mutations in sperm cells

Explanation:

A trisomy is an alteration in the chromosome number (i.e., an aneuploidy), and occurs when a cell receives three chromosomes instead of two. The risk of aneuploidies -including trisomies- increases with the mother's age due to the fact that older eggs have a higher chance of dividing unequally, thereby leading to an imbalanced number of chromosomes between daughter cells. Moreover, a point mutation is defined as a genetic modification where a single nucleotide is changed in the DNA sequence. It has been shown that point mutations in children are determined to a large extent by the father’s age, which are due to mutations in germline cells (i.e., sperm cells) that were passed to the progeny. A child born from a father who is 20 years old exhibits on average 40 point mutations, whereas a child born from a father who is 40 years old has typically twice the point mutations on its genome.


Related Questions

What is the structure shown in the figure?



Proteins

Nucleic acids

Carbohydrates

Lipids

Answers

Answer:

2nd to last one

Explanation:

Answer:

It is a protein.

Explanation:

It is an amino acid structure, which make up proteins.

Which of the following bones are considered to be the MOST proximal?
metatarsals
clavicle
ulna
olecranon

Answers

Answer:

Of the group of bones mentioned, the most proximal is the clavicle, which is part of the shoulder girdle.

Explanation:

Proximal is a reference term used in anatomy to indicate the structures that are closest to the center of the body.

The bones mentioned -clavicle, olecranon, ulna and metatarsals- are related to the function of the limbs. The clavicle is the closest bone to them, located between the neck and the thorax, on each side of the midline of the body.

Regarding the other options, other bones are distal, as they move away from the center of the body. In order from less distal to more distal they are found:

Olecranon, which is a bone eminence of the ulna, in the upper limb. Ulna or cubitus, which is part of the bones of the forearm. Metatarsals are the bones that form part of the foot.

Warm-Up Activity - Scenario: You are on a desert island. Alone. You must survive. The island has only one food source

that you've found: pineapples. It takes you 2 hours to harvest and cut up 1 pineapple (you have no knife!). You also want

to build your shelter. Each piece takes you 3 hours to build.

You have only 12 hours of sunlight and need to complete your tasks by sundown.

How will you spend your hours? Record your decision on your student notes.

Warm-Up-

1. Think back to the Warm Up activity. Why did you spend your hours the way you choose?

2. Whatlimits did you face? What tradeoffs did you make?

3. How does scarcity (limited resources) affect our economy and ability to produce?

Ce

Answers

Answer:

Explanation:

first day at the desert most of my hours will be spent making shelter for safety and then in the evening hunting is done for food.

Pineapple has an alternative way of opening without knife, which is to hit and roll on the ground severally exerting little force this allow the hard shell to be loosely packed and can be easily removed with hands from each box on the pineapple body.

The best way to maximize time is to do the most important and tedious work first.

Having limited tools to work with because it is a desert is a major challenge

Scarcity have put some industries on hold, many could not produce in large quantities because of Scarcity. The available resources is what is shared among many which makes its unavailable.

It affects the economy in terms of production and expected yield and return, it also affects people's standard of living.

Fats are the predominant forms of a class of biological molecules called _______, which also includes fatty acids and steroids, among other molecules. These biomolecules readily dissolve in _______ solvents such as hexane and chloroform. Because of their insolubility in water, fats and other biomolecules in this class are said to be_______. Triacylglycerols, also known as triglycerides, are a storage form of fat found in adipose tissue that consist of glycerol bound to_______. These fats are categorized based on the bonding of the carbon atoms in the chain. Fats that contain chains with no double bonds are classified as_______ , whereas those that contain double bonds in the carbon chain are _______.

Answers

Answer:

1. Lipids

2. Non-polar

3. Non-polar

4. Fatty acids

5. Saturated fats

6. Unsaturated fats

Explanation:

LIPIDS are one of the four major biomolecules in living systems. A form of lipids are fats which constitute most lipids i.e. predominant. Lipids also includes fatty acids, steroids and other molecules.

Lipid biomolecules readily dissolve in POLAR solvents such as hexane and chloroform. Because of their insolubility in water (polar solvent), fats and other biomolecules in this class are said to be NON-POLAR.

Triacylglycerols, also known as triglycerides, are forms of fat that is composed of a glycerol molecule bound to three molecules of FATTY ACIDS.

Based on the bonding of the carbon atoms in the chain, fats that contain chains with no double bonds are classified SATURATED FATS, while those that contain double bonds in the carbon chain are UNSATURATED FATS.

SELECT ALL THAT APPLY. Which two elements make up the water cycle?*
2 points
Carbon
Sulfer
Nitrogen
Gold
Phosphorus
Hydrogen
Oxygen
Helium
This is a required question

Answers

Answer:

Maybe

hydrogen and oxygen

Is this DNA or RNA????

Answers

rna your welcome person

amino acid structure: the only part of the amino acid structure that varies between the amino acids and makes each type unique is

Answers

Answer:

The side groups are what make each amino acid different from the others. Of the 20 side groups used to make proteins, there are two main groups: polar and non-polar. These names refer to the way the side groups, sometimes called "R" groups, interact with the environment.

Explanation:

describe the relationship between CO2 in the seawater and the pH of the seawater

Answers

Answer:

As the amounts CO^2 in the sea increase, it causes the acidity of the pH increase as a result

Explanation:

Which among the following mineral groups, if any, contain silicon: halides
carbonates or sulfides? Explain.​

Answers

Answer:

The correct answer is: none of these mineral groups contain silicon.

Explanation:

The only minerals that contain silicon are the Silicates, for example, SiO2 (silica).

Halides are minerals that consist of a combination of elements from the seventh group that can form salts (like fluorine or chlorine), with other elements such as calcium and sodium. For example: NaCl (sodium chloride).

Carbonates are compounds that contain carbon and oxygen, for example, CaMg(CO3)2 (dolomite).

Sulfides consist of sulfur with another element. For example: ZnS (zinc sulfide).

Students in a science class visited four local ecosystems. The students observed the species present in each ecosystem and recorded their observations in the table.


Based on these observations, which ecosystem is likely to be the least sustainable?

A.Ecosystem 1, because it has the fewest species
B.Ecosystem 2, because it includes both aquatic and terrestrial species
C.Ecosystem 3, because it has few predators
D.Ecosystem 4, because it supports many animals

Answers

the answer is A

this is because in ecosystem 1 there are only predators and no other species are observed. therefore predators have less food to eat thus they will die of hunger or move to another ecosystem

This is because in ecosystem 1 there are only predators and no other species are observed. therefore predators have less food to eat thus they will die of hunger or move to another ecosystem.

What is Ecosystem?

An ecosystem is a geographic area where plants, animals, and other organisms, as well as weather and landscape, work together to form a bubble of life.

Ecosystems contain biotic or living, parts, as well as abiotic factors, or nonliving parts. Biotic factors include plants, animals, and other organisms. Abiotic factors include rocks, temperature, and humidity.

Every factor in an ecosystem depends on every other factor, either directly or indirectly. A change in the temperature of an ecosystem will often affect what plants will grow there, for instance.

Therefore, This is because in ecosystem 1 there are only predators and no other species are observed. therefore predators have less food to eat thus they will die of hunger or move to another ecosystem.

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The zika virus was first identified in Uganda in 1947. The virus is transmitted from person to person by a bite from a mosquito. It is commonly carried by the Aedes mosquito which is prevalent throughout Central Africa. The virus has more recently spread to the Americas (South, Central, and now North) and is expected to spread to Europe. There is a concern that the virus may reach epidemic proportions. Zika virus is related to yellow and dengue fever. Common symptoms are low grade fever and a distinctive skin rash and other symptoms include vomiting, headache, and muscle and/or joint pain. Pregnant women should avoid traveling to areas known to have zika virus present because the virus is known to cause microcephaly and developmental difficulties related to the central nervous system. Based on the paragraph above, class discussions, and other VALID (be careful with your selection of e-materials! CDC – Center for Disease Control is a good place to start) sources of information please answer the following questions.
1. State a reason why the virus has spread to the Americas and likely to spread to Europe.
2. Define the term microcephaly.
3. What bones of the fetal skull would be affected by zika? Specifically, what area of the CNS is not fully developed in microcephalic individuals.

Answers

Answer:

1. It is a highly contagious disease transmitted from person to person and thereby it is expected that infected persons carried the virus to America  

2. Microcephaly is a serious birth defect where a baby’s head is much smaller than expected.

3. Occipital bone. CNS malformations: ventriculomegaly, parenchymal and periventricular calcifications and cortical migration anomalies

Explanation:

The Zika virus (Flaviviridae) causes a contagious disease and it is transmitted by Aedes mosquitoes, which are also the main vectors of the dengue virus. Microcephaly is a condition where the baby’s brain has not developed properly during pregnancy, and it has been shown that this birth defect is associated with the Zika virus. During 2015 in Brazil, the incidence of infants with microcephaly born from mothers that contracted this disease during pregnancy was higher, thereby suggesting an association between both conditions. Baby health problems associated with Zika infection include microcephaly (skull partially collapsed), joints with limited motion, etc.

1. The increase in the reproductive success of a species will have the greatest impact on
the-

Answers

Answer:

The increase in the reproductive success of a species will have the greatest impact on the prey of the animal.

Explanation:

The prey's population will decrease because there are more animals needing it to survive.

An element that is an alkali metal is what?

Answers

Answer:

very reactive

Explanation:

They form salts and alkali (acid-neutralizing) compounds such as baking soda. In pure form, they are very soft metals which catch fire on contact with water. (These metals are not found free in nature). These elements are Lithium(Li), Sodium(Na), Potassium(K), Rubidium(Rb), Cesium(Cs), and Francium(Fr)

Which products do not have scientific studies supporting their claims to be beneficial when used?

A. Cofactors and coenzymes to support enzyme function
B. Lactase enzymes used in milk sugar digestion
C. Enzyme that aids in the digestion of oligosaccharides
D. Enzymes to promote immune system function

Answers

Answer:

B (not sure)

Explanation:

sorry if I'm wrong (which I'm probably). Research more on the internet. Maybe take a look at ur school book

When ice and snow move overland in compacted large quantities, they erode the soil and can change landforms. Which object creates this type of erosion?

Answers

I believe the answer is Icebergs

why can b blood donate to AB blood?? ​

Answers


People with type AB+ blood are universal recipients because they have no antibodies to A, B or Rh in their blood and can receive red blood cells from a donor of any blood type. Plasma transfusions are matched to avoid A and B antibodies in the transfused plasma that will attack the recipient's red blood cells.

Answer:

Type B contains the B antigen.

This type is relatively rare (second only to AB). It contains the B antigen on its red blood cells, and the A antibody (to attack A antigens) in its plasma

Explanation:

Which of the following is an example of a nonmetallic mineral?
a sulfur
b. lead
c. aluminum
d. gold
Please select the best answer from the choices provided
A B C D

Answers

Answer:

a. sulfur

Explanation:

Sulfur is an example of a nonmetallic mineral

Non-metallic mineral

Non-metallic minerals are the minerals that do not contain metals, eg limestone, mica, coal etc. Such materials lack metallic characteristics like good electric and thermal conductivity, luster, rigor and malleability.

Sulfur is a non-metallic element with atomic number 16. It is considered as non metal because:

It is poor conductor of heat and electricity. Its density is lower than that of all metals. The electronegativity of sulfur is very high as compared to other metals. It is multivalent atom which is tasteless and odorless.

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Please somebody help me !

Answers

Answer:

Water molecule, Glucose molecule,Cell, Chloroplast, Leaf

Explanation:

Answer:

Chloroplast

Cell

Water molecule

Glucose molecule

Leaf

Explanation:

Hope this helps

What enables neighboring water molecules to hydrogen bond with eachother

Answers

Answer:

Hydrogen bond

Explanation:

The covalent bonds between the oxygen and the hydrogen atoms result from a sharing of the electrons. This is what holds the water molecules themselves together. The hydrogen bond is the chemical bond between the water molecules that holds the mass of molecules together.hope the answer was helpful, mention me as brainliest.
I think the molecules are polar, with each partial positive end (Hydrogen) of one molecule attracted to the partial negative end (Oxygen) of another molecule. The cohesion of water molecules and its high surface tension hold water in droplets.

Why does Earth get more energy from the sun than from all the other stars in the universe combined?
The sun is much hotter than the other stars.
The sun is much more dense than the other stars.
The sun is much larger than the other stars.
The sun is much closer than the other stars.

Answers

Answer:

D

Explanation:

the only thing that sets our sun apart from others is that its closer

D the sun is closer than other stars

Which adaptation helps the arctic fox survive by allowing it to sneak up on its prey undetected?
a bushy tall
b large litter size o ability to eat a wide variety of foods
c white winter coat and brown summer coat​

Answers

Answer:

c - white winter coat and brown summer coat

Explanation:

The white winter coat blends in with the snow during the winter. Similarly, the coat changes to brown once it is summer so that the white coat doesn't stick out.

Which factor does the moment magnitude scale estimate?

Answers

Answer:

Energy released

Explanation:

The moment magnitude scale estimates the total energy released by an earthquake.

Answer: The answer is Energy Released

Explanation: I Just did this Question.

I need help ASAP please

Answers

Answer:

D

in both the Eastern and Western Hemisphere

Explanation:

Which of these choices is a risk of replacing a coal-burning power plant with
a nuclear power plant?
A. Improper storage of radioactive waste
B. Reduced greenhouse gas emissions
C. Improved respiratory health of residents
OD. New jobs created in the nuclear power plant

Answers

A) The reason why if you do not properly handle the waste you’ll have chemical and radioactive waste going into your water supply or grounds and slowly might effect your heath or it’ll effect it quickly.

The statement that is a risk of replacing a coal-burning power plant with a nuclear power plant is improper storage of radioactive waste.

What is nuclear power plant?

Nuclear power plant is a power plant that obtains its primary energy from the heat generated in nuclear reactions.

Nuclear source of energy is a renewable source while a coal source of energy is nonrenewable.

However, nuclear radiation releases radioactive particles indiscriminately into the environment when used.

Therefore, the statement that is a risk of replacing a coal-burning power plant with a nuclear power plant is improper storage of radioactive waste.

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Which products do not have scientific studies supporting their claims to be beneficial when used?

A. Cofactors and coenzymes to support enzyme function
B. Lactase enzymes used in milk sugar digestion
C. Enzyme that aids in the digestion of oligosaccharides
D. Enzymes to promote immune system function

Answers

Answer:

i think it might be b

Explanation:

A key difference between plants and animals is the method by which glucose is obtained to be converted to ATP. By what process do most plants obtain glucose for energy?

A. Photosynthesis

B. Ingestion of organic material

C. Aerobic cellular respiration

D. Anaerobic cellular respiration

Answers

Answer:

A. Photosynthesis

Explanation:

Plants absorb co2 and water. Through photosynthesis they create glucose.

You remove pus from a wound and try to identify the pathogen multiple ways. The multi-locus gene tree showed your organism was most closely related to Streptococcus pyogenes but the 16S tree said it was most closely related to Streptococcus pneumoniae. Describe why this might be the case and other ways you should try to identify this organism.

Answers

Answer:

It occurs because phylogenetic analyses based on the 16S rRNA gene sequences may have insufficient resolution for distinguishing between closely related species

Another genomic method for streptococcal identification is whole-genome analysis (WGS)

Explanation:

The phylogenetic analysis of the highly conserved 16S rRNA gene sequences has recently been used to distinguish between prokaryotic species. However, this gene sometimes may show low resolution to distinguish between closely related species, and it has been suggested potential horizontal transference of rRNA genes. Moreover, multi-locus sequence analysis (MLSA) has also been used to identify species. MLSA analysis consists of analyzing simultaneously different genes and this technique has shown to have a high capacity for establishing relationships between species within a genus or genera within a family. Finally, whole-genome analysis (WGS) is the most powerful tool for distinguishing between closely species. WGS is a technique that provides a very high resolution which is based on the analysis of large-scale genome sequencing data generated by next sequencing generation (NGS) technologies.

what is a CER please help !!!!!!!

Answers

Answer:

Claim-Evidence-Reasoning

Explanation:

hope it helps

Answer:

CER(S) Stands for Claim, Evidence, Reasoning, Science

Explanation:

The 1st part of CER(S) is a CLAIM. A claim is a simple, single sentence that answers a question. Your claim is a statement about what you believe to be true about that question. Your claim must be accurate, clear, and exact. Your claim should be the first sentence in your explanation. Your claim should ONLY answer the question – do not explain your answer at this point.

The 2nd part of CER(S) is EVIDENCE. Evidence consists of data and/or results that can be used to support the claim. Evidence must be explicitly stated in sentence form and cannot merely be referenced. To adequately support a claim, the evidence must be appropriate (relevant to the question) and sufficient (enough provided to be convincing).

The 3rd part of CER(S) is the REASONING. Reasoning ties the evidence to the claim and explains why the evidence supports your claim.  In this section you discuss why the evidence that you provided is important and relevant to your claim.  

The 4th and final part of CER(S) is the SCIENCE. Your teacher may not ask you to provide the supporting science for every CER(S) question – that is why the S is in parentheses. If you are asked to provide the science that supports your claim, then you need to discuss the relevant science and how it supports your claim.

Consumer surplus is the area

Answers

Answer:

what's the question????

Which stroke or style is usually swum in a warm-up?

Answers

Answer:

The #1 stroke referred to in the warm-up is the stroke you're focusing on in the upcoming session, your main event this session. After sitting around for an hour or so waiting for your event, it's important to wake up the muscles and increase the blood flowing through your body again.

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The [ Select ] the distance between the effort force and the fulcrum of a lever, the [ Select ] force is needed to complete the work. The [ Select ] the distance between the effort force and the fulcrum of a lever, the [ Select ] the mechanical advantage, making the work easier. Given the equation 5(-2x -10) = 25(x + 1), solve for the value of x that will make the equation true. in mutualism neither organism benefits true or false Read the passage.excerpt from The Story of My Lifeby Helen KellerAt the age of 18 months, Helen Keller was rendered deaf and blind. Unable to read, write, or speak, it was thought that Helen would never be able to communicate. "The Story of My Life" describes Helen's education with Anne Sullivan and the unorthodox teaching methods that enabled her to learn how to communicate and thrive.We read and studied out of doors, preferring the sunlit woods to the house. All my early lessons have in them the breath of the woodsthe fine, resinous odour of pine needles, blended with the perfume of wild grapes. Seated in the gracious shade of a wild tulip tree, I learned to think that everything has a lesson and a suggestion. The loveliness of things taught me all their use. Indeed, everything that could hum, or buzz, or sing, or bloom had a part in my educationnoisy-throated frogs, katydids and crickets held in my hand until forgetting their embarrassment, they trilled their reedy note, little downy chickens and wildflowers, the dogwood blossoms, meadow-violets and budding fruit trees. I felt the bursting cotton-bolls and fingered their soft fiber and fuzzy seeds; I felt the low soughing of the wind through the cornstalks, the silky rustling of the long leaves, and the indignant snort of my pony, as we caught him in the pasture and put the bit in his mouthah me! how well I remember the spicy, clovery smell of his breath!Sometimes I rose at dawn and stole into the garden while the heavy dew lay on the grass and flowers. Few know what joy it is to feel the roses pressing softly into the hand, or the beautiful motion of the lilies as they sway in the morning breeze. Sometimes I caught an insect in the flower I was plucking, and I felt the faint noise of a pair of wings rubbed together in a sudden terror, as the little creature became aware of a pressure from without.Another favourite haunt of mine was the orchard, where the fruit ripened early in July. The large, downy peaches would reach themselves into my hand, and as the joyous breezes flew about the trees the apples tumbled at my feet. Oh, the delight with which I gathered up the fruit in my pinafore, pressed my face against the smooth cheeks of the apples, still warm from the sun, and skipped back to the house!Our favourite walk was to Keller's Landing, an old tumbledown lumber-wharf on the Tennessee River, used during the Civil War to land soldiers. There we spent many happy hours and played at learning geography. I built dams of pebbles, made islands and lakes, and dug river-beds, all for fun, and never dreamed that I was learning a lesson. I listened with increasing wonder to Miss Sullivan's descriptions of the great round world with its burning mountains, buried cities, moving rivers of ice, and many other things as strange. She made raised maps in clay, so that I could feel the mountain ridges and valleys, and follow with my fingers the devious course of rivers. I liked this, too; but the division of the earth into zones and poles confused and teased my mind. The illustrative strings and the orange stick representing the poles seemed so real that even to this day the mere mention of temperate zone suggests a series of twine circles; and I believe that if any one should set about it he could convince me that white bears actually climb the North Pole.Part AWhat does Helen Keller's word choice in her description of her lessons with her teacher, Anne Sullivan, reveal about Keller? A. Her lessons are easier for her when she learns them outdoors. B.She feels connected to the natural world despite her lack of sight. C.The natural world holds many mysteries for her that she wishes to solve. D. She no longer misses her sense of sight when she is outside.Question 2Part BHow does the word choice in paragraph 1 help to develop the idea in Part A? A. Keller includes comparisons of her education to things that occur naturally in the wild. B. Keller includes descriptions of natural things that she can touch and smell. C. Keller includes the phrase breath of the woods to show that the natural world is living. D.Keller includes the sentence The loveliness of things taught me all their use to show that nature is a teacher. On a farm, the farmer decides to give pizza to her 15 ducks as a special treat. She orders 3 pizzas, and the total price is $23.46. What is the unit price of each pizza? (4 points)Group of answer choices$70.38$5.00$1.56$7.82 Vhy did the color of the peppered moth change?A.The moths' life cycle changed, B.The environment changedC.The amount of variation in the moth population changedD.The number of individual moths in the population changed, Question 20 of 25Einstein's theory of general relativity was published in 1916. It became fullyaccepted by scientists in the 1960s and is currently the best explanation ofgravity. Why did it take so long to become an accepted scientific theory?A. The scientific community requires a certain amount of time beforea theory can be accepted.B. No scientific laws could be found to validate the theory.C. More evidence needed to be gathered to validate the ideas in thetheory.D. Einstein's theory was difficult for many people to understand.SUBMIT who is the governor of arizona and how taxes been used in phoenix? you are a contractor installing a brick sidewalk. The portion of the sidewalk will occupancy and area of 100 feet long by 4 feet wide. Each brick will occupy and area 8 inches long by 4 inches wide what is the minimyn nuber of bricks will you need to occupy this area Please answer these giving brainliest to the first right person. 20 points. Someone who said that they did not hire Catholics would be violatingwhich amendment?A. 1stB. 2nd 4. 4th5. 5th Which of the following is likely to occur immediately as a result of new legislation regarding transition programs for veterans of the Afghanistan War?Choose 1 answer:Choose 1 answer:(Choice A)AThe Department of Veterans Affairs will use its authority to decide how to implement the law effectively.(Choice B)BMilitary experts will make recommendations to Congress on how much money they should spend creating these programs.(Choice C)CStates will create several job training programs to help veterans find jobs as they transition out of the military.(Choice D)DThe House Committee on Veterans Affairs will meet with recipients to determine the effectiveness of the law. The most common cause of foodborne illness is How did the Native weapons change? Why was it important to connect the Washington Territory to the rest of the country? Question 3 options:Because Washington offered an abundance of outdoor activities. Because Washington offered an abundance of natural resources. Because Washington was lacking in natural resources. Because Washington's workforce was largely migrant. 17+7j=87 What does j equal??????? what is the meaning of drama 2. What arguments against women's suffrage do you see in these cartoons? 3x-5=x+1Helpppppppppppp 8p+5=-6p+1 what's the answer to this equation?